Rheumatoid Arthritis: A Life-threatening Condition?

Condition - Rheumatoid Arthritis: A Life-threatening Condition?

Rheumatoid Arthritis: A Life-threatening Condition?

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Rheumatoid arthritis is the most common inflammatory form of arthritis and affects approximately two million Americans. It is an autoimmune disease. Autoimmune diseases are characterized by abnormal function of the immune system. For whatever infer (and that infer is still unknown), the immune principles attacks healthy tissue. In rheumatoid arthritis, joint tissues such as ligaments, tendons, and muscles, are attacked and come to be inflamed. Symptoms that produce comprise painful, swollen, tender joints. The small joints in the hands and feet are the most generally affected. Other prominent symptoms comprise fatigue and stiffness.

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Rheumatoid arthritis is a systemic disease meaning it attacks many separate organ systems. One organ principles that can be affected are the blood vessels. This inflammation of blood vessels is called vasculitis. It is especially hazardous because vessels carry blood throughout the body: to the brain, lungs, skin, kidneys, and heart. "Shutdown" of organs occurs. Why? As the inflammation of the blood vessels progresses, the blood vessels are no longer able to transport blood.

Vasculitis due to rheumatoid arthritis can lead to heart attack and stroke. (Roman Mj, et al. Preclinical Carotid Atherosclerosis in Patients with Rheumatoid Arthritis. Annals Int Med 2006; 144: 249-256)

A sidebar to this is the eye involvement that can occur. Inflammation of the sclera- the white part of the eye- can lead to blindness as a ensue of perforation or hemorrhage.

An fascinating side light to this is that some studies furnish evidence that long-term smoking contributes to the immune system's malfunctioning. This most likely explains why smoking is linked with increased severity of the disease. This is also why smoking and rheumatoid arthritis make a terrible combination. Smoking causes premature atherosclerosis and rheumatoid arthritis does also.

If untreated, rheumatoid arthritis significantly shortens life span by an average seven to eight years. It increases the risk for heart attack and stroke. Sixty percent of untreated patients are disabled and dependent on others to take care of them within 10 years.
One other factor that contributes to the shortened lifespan is the increased incidence of lymphoma that occurs in patients with Ra.

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